Currently, LFDs that provide such multiplexing are constructed either by laminating  together  individual LFDs or by multiplexing within a single flow-path. Such devices have inherent drawbacks such as increased device dimensions and therefore need for larger sample volumes, and an undesired interference between different detection sites.

We invented a novel solution to overcome both these limitations – a multi-path LFD created via the precise partition of the flow-path of a single LFD using a laser direct-write (LDW) technique. The multiple flow-paths allow individual detection of different analytes in each of the separated channels.